CLA 4,500 Review – Purity Labs Weight Loss Supplement with Safflower Oil

Can safflower oil help you lose weight. Purity Labs CLA 4500 suggests it can help weight loss and appetite control. Read the CLA 4500 review and find out how it works and how it compares to other diet pills.

Purity Labs CLA 4,500 review

CLA 4500 Review Summary: Purity Labs CLA 45,00 provides a standard dose of conjugated linoleic acid but that is all. There are no other active ingredients for losing weight. If you are set on buying and using CLA supplements, this option is probably no better or worse than a lot of the alternatives.

Pros: A well dosed conjugated linoleic acid formula, respected manufacturer, not expensive.

Cons: Limited weight loss potential, nothing to set it apart from other CLA pills, mixed user reviews and comments.

If you are serious about losing weight we recommend PhenQ natural fat burner – a multi action supplement that cans also reduce food cravings and block a portion of fat from your food from being digested.

What is Purity Labs CLA 4,500?

CLA 4500 is a dietary supplement manufactured in the USA for Purity Labs. The company also distributes several other health and wellness products including fish oil capsules and an elderberry supplement that’s fortified with zinc and vitamin C.

As the name suggests, CLA 4500 is an oral supplement that provides conjugated linoleic acid (CLA). Like most competing products, CLA 4500 provides CLA taken from safflower oil, and to Purity Lab’s credit, it’s using a non-GMO version. Unfortunately, it’s opted to lock the oil inside a soft gel capsule made from gelatin. That’s going to rule out a lot of potential customers who are vegan or vegetarian.

Purity Labs is primarily marketing CLA 4500 as a weight management supplement but it makes several other claims for the product as well.

CLA 4500 from Purity Labs

CLA 4500 Benefits

  • Supports Weight Management
  • Boosts Metabolism
  • Provides Appetite Control
  • Improves Lean Muscle Mass
  • Enhances Mood and Wellbeing

All the above are claims that are common to many other weight loss supplements.

However, Purity Labs also claims its product provides help in other areas:

  • Heart Function
  • Joint Mobility
  • Cognitive Function

How to Use CLA 4500

The dose is two to three capsules per day, taken with meals. Each bottle of CLA 4500 provides 180 softgel capsules, so it’s going to last a while.

Although Purity Labs does not mention this, it’s inadvisable to take safflower oil supplements during pregnancy. It may bring on menstrual periods and cause the uterus to contract.

Safflower oil supplements can also present risks to people who suffer from bleeding problems or diabetes.

Purity Labs CLA 4,500 Ingredient Profile

Each softgel capsule contains 1500 mg of non-GMO safflower oil that’s 80% CLA.

If you take the maximum serving of three capsules per day, you will get 4,500 mg of safflower oil. Once you know that, the name of the product suddenly makes sense.

How Does the CLA 4,500 Formulation Work?

Purity Labs doesn’t explain how its supplement works but it points out CLA supplements can be a safe alternative to diet pills, which often have undesirable side effects.

That statement is not totally without merit. A lot of diet pills are loaded with stimulants, and high doses can cause side effects.

CLA 4500 is an oil capsule. It has no stimulants; or any other active ingredients for that matter. It is made from non-GMO safflower oil.

However, there are some very good diet pills that are not overly reliant on stimulants and will certainly offer a greater level of weight loss support than CLA 4500 is capable of doing.

Despite the claims Purity Labs make for CLA 4500, it’s unlikely to do much to defeat hunger. Nor is it likely to be any good for fighting fatigue.

Will Purity Labs CLA 4,500 provide any weight loss support in other areas? The best way to answer that question is to take a closer look at the abilities of the key ingredient – conjugated linoleic acid (CLA).

Here we deep dive into the ingredients contains in Purity Labs CLA 4,500

Purity CLA 4500 Ingredient Potential

Although the CLA in CLA 4500 is plant-based, safflower oil is not the only source. CLA is also present in many meat and dairy products. The meat of grass-fed cows is particularly good.

There are several different forms of CLA but cis-9, trans-11 and trans-10, cis-12 are the two most important ones.

Cis-9, trans-11 is a form that occurs naturally in food. Trans-10, cis-12 is the type you get from supplements. It’s hard to see this option as being natural because it’s a chemically altered form of linoleic acid created from safflower oil or certain other vegetable oils.

This form of CLA does not occur naturally in nature. It’s not nearly so beneficial as the form you get from food.

CLA and Appetite

A limited amount of evidence suggests CLA may increase satiety and control hunger. However, as with any other ingredient, the appetite suppressing ability of CLA is dose-dependent and research suggests it will require quite a hefty dose.

The people who took part in one study were getting 1.8 grams to 3.6 grams of CLA a day. CLA 4500 provides 4.5 grams per day. That’s a little more, so it’s possible CLA 4500 may help with hunger. In theory anyway. Customer reviews fail to back this up.

CLA and Weight Loss

None of the people who took part in the study mentioned above lost any weight. The same is true for the participants in a lot of other studies exploring the weight loss benefits of CLA.

Nevertheless, a clinical review of 18 controlled trials suggests 3.2 grams of CLA per day can provide modest fat loss. How modest? 0.2 pounds per week.

If you are not impressed by that, we are not surprised, and it gets worse. After six months of supplementation, fat loss appears to plateau for up to two years.

CLA and Muscle Mass

Some of the studies that are supportive of using CLA supplements for weight loss suggest it may also deliver improvements in muscle mass. For this reason, CLA is often included in sports supplements and fat burners aimed at bodybuilders.

People following low-calorie diets often lose a little muscle along with their fat. For anyone who has worked hard to build their muscles, this is highly undesirable. Its possible CLA may help but the way the compound affects muscle metabolism is not completely understood.

Additional CLA Benefits

What other benefits does CLA offer? That depends on who you talk to. There are a lot of stories doing the rounds.

Some of them have scientific founding, others do not. In fact, some supplement manufacturers appear to be making it up as they go along.

People who get plenty of CLA from their food appear to be less susceptible to certain diseases, including type 2 diabetes. But remember, the form of CLA present in food is different from the CLA that’s made from safflower oil.

Some research suggests CLA may be good for reducing joint pain so, when Purity Labs make this claim for CLA 4500, it’s not totally unfounded.

If you search long enough and hard enough, you can find a few studies that link CLA with various mental benefits but, overall, it’s a vastly overrated ingredient.

A clinical review exploring the various claims made for CLA, along with relevant research suggests ” CLA is not eliciting significantly promising and consistent health effects so as to uphold it as neither a functional nor a medical food.”

Who are we to disagree with the experts. Even if we wanted to, we could not. Our research suggests the same.

Purity Labs CLA 4,500 Customer Reviews

Customer reviews are mostly good but reports of weight loss are few and far between. Reviewers just tend to leave comments like “works great with healthy food choices” and “seeing a difference with CLA.”

Negative reviews often mention side effects but there are plenty of people who simply say the product does not work. A lot of customers also complain about receiving capsules that had partially melted and clumped together in the bottle.

A few positive CLA 4,500 customer reviews:

“great product and great company. I ordered from Amazon and it arrive 2 days later. I am into my 3rd month and already showing signs of weight loss. My appetite is diminishing.’

I started using CLA4500 after a friend suggest them. I am so glad I took her advice. I usually can’t resist cakes and candy. Not anymore.

Some Purity Labs negative comments:

I wish I had never bothered buying CLA4500. I have not lost any weight whatsoever. My cravings for sugary food is still the same. I am disappointed with my CLA4,500 results.

I can honestly say I do not notice any effect at all, my weight is unchanged – I am still over weight and still can’t resist snacking.

Known Side Effects of Purity Labs CLA 4500

Customer reviews mention several side effects:

  • Indigestion
  • Headaches
  • Dizziness
  • Heart flutters/rapid heartbeat
  • High blood pressure

Reports of headaches and high blood pressure come up again and again. This is surprising because safflower oil is not normally associated with side effects such as these.

WebMD (trusted site) doesn’t mention any side effects at all. It states safflower oil is likely safe for most people when taken by mouth. Notable exceptions include women who are pregnant or nursing a child, people with bleeding problems, diabetics, and anyone who is allergic to ragweed and similar plants.

Where to Order Purity CLA 4,500 – Purchasing Options and Considerations

CLA 4500 is available from the manufacturer’s website and from and costs $23 – $25 per bottle.

The official site offers modest discounts for placing larger orders, with the best deal going to customers who order a 3-pack and pay $20.97 per bottle.


CLA 4500 allegedly has a 365-day money-back guarantee but some customers claim to have had difficulties getting Purity Labs to honor it.

Purity Labs CLA 4500 Review Conclusion

CLA 4500 provides a decent dose of conjugated linoleic acid. That’s all it does. There are no other active ingredients. If you are keen on CLA supplements, this option is probably no better or worse than a lot of the alternatives.

However, all the customer complaints about receiving capsules that had clumped together suggest, in this case, there may be some quality issues.

When you ignore the claims being made by the companies selling CLA supplements and focus on the research, it becomes clear, CLA is not the wonder ingredients thes companies would have you believe.

Nevertheless, it appears to have limited potential as a weight management aid. Just don’t expect rapid weight loss.

The bottom line is, if you are thinking of buying Purity Labs CLA 4500 and using it as a diet pill, you are likely to be disappointed. There are alternative options that have more to offer. We suggest you choose one of those instead.

Similar Supplements to Purity Labs CLA 4500

Here are some weight management pills that work in a similar way to CLA 4500

  • PhenQ – an appetite suppressant, fat burner and fat blocker that is highly effective at helping users lose weight and keep it off
  • Golo Release – a natural weight loss supplement that can help weight loss by reducing hunger and food cravings.
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about the author

Henry Washington BSc, BSc, MA, PhD. Fascinated with the study of human behavior, and how this affects our day-to-day lives. Has read more books on the subject than he can count and has an extensive collection of academic papers to match. Published in the following journals: Nature, Journal of Cognitive Neuroscience, Trends in Neurosciences, Neuroscience & Biobehavioral Reviews, Brain research reviews and Cerebral Cortex.