Lipo-6 Black Intense Ultra Concentrate Review

Review of Lipo 6 Black Intense Ultra Concentrate is a fat-burning supplement explaining how it works, what’s in it and comparisons to other similar fat burners.

Lipo 6 Black Intense Review

Lipo 6 Black Intense Review Summary: A fat burner suitable for men and women made by Nutrex. A striking yellow and black packaging houses an intense fat burning pill that doesn’t really live up to expectation in our opinion.

Pros: Made by a reputable company, some decent ingredients, not expensive.

Cons: Very stimulant based (The caffeine content alone far exceeds expert recommendations), mixed customer reviews.

It is our recommendation to choose multi action fat loss supplement such as PhenGold. It is currently the fat burner that is setting the bar.

Lipo 6 Black Intense Ultra Concentrate is a fat-burning supplement manufactured in Florida by Nutrex Research. The company was founded in 2002 and achieved instant success with its first product – a liquid-center fat-burning capsule called Lipo-6.

Over the years, Nutrex Research has expanded its supplement line considerably and, in addition to protein powders and amino acid supplements, it presently has more versions of Lipo-6 than you can shake a stick at.

The vast majority of them are variations on Lipo-6 Black.

There’s a Lipo-6 Black for women, a stim-free version, and even options for keto dieters and people who want to burn fat while they sleep. 

However, like a lot of supplement companies, Nutrex Research appears to be mainly targeting bodybuilders and other sporty individuals who like to train. Due to their stimulant-rich nature, most of the Lipo-6 supplements will be too hardcore for the average dieter.

Lipo 6 Black Intense Ultra Concentrate Benefits

  • Intense one pill only fat burner
  • Powerful thermogenic metabolizer
  • Takes fat burning to the extreme
  • Provides intense energy
  • Delivers maximum appetite control

According to Nutrex Research, the formulation is so extreme the effects are noticeable in minutes. The formulation has several stimulants in it, so that may be true but customers reviews suggest the effects some people experience are more unpleasant than helpful.

How Does Lipo 6 Black Intense Ultra Concentrate Work?

Lipo-6 Black Intense Ultra Concentrate is a thermogenic fat burner. It provides ingredients that increase thermogenesis and metabolism.

Thermogenesis generates heat in the body. The supplement encourages your body to become a little warmer. When this happens, you lose extra energy as heat. This increases metabolism.

Human metabolism encompasses all the chemical and biological processes that sustain life. When we talk about metabolism in relation to fat loss, we mean energy metabolism.

When the body is at rest, it only needs to power respiration, digestion, thought formation, and all the other processes that are necessary to maintain life.

However, physical activity requires extra energy, so it increases “metabolism.” The more active we become, the faster our metabolism becomes. Hard exercise requires a lot of energy. That’s why physical activities, such as jogging, can be so good for supporting weight loss.

Some natural ingredients, increase metabolism. When we consume supplements that provide them, it causes us to lose extra energy. If the amount of energy entering the body (from food) is sufficiently low, thermogenic fat burners can help us to lose more weight than we could with diet and exercise alone.

Many ingredients, including green tea and cayenne, increase metabolism and thermogenesis. Caffeine and similar stimulants do it too.

Lipo-6 Black Intense Ultra Concentrate is heavily reliant on stimulants to boost metabolism. Although this can be effective, stimulant-rich fat burners have a great potential for side effects. That’s why most of the best fat burners use alternative ingredients instead and only provide stimulants in sensible amounts to boost energy and prevent fatigue.

How to Use Lipo-6 Black Intense Ultra Concentrate

Lipo-6 Black Intense Ultra Concentrate is for healthy adults who are aged 18 or over. It’s not for women who are pregnant or for nursing mothers.

People who have existing health problems or are using medication will need to check with their doctor before using this supplement.

The dose is one capsule in the morning and a second one during the afternoon. For best results, customers are advised not to take the capsules with food and at least 45 minutes before meals.

Nutrex Research also stresses it is unwise to take Lipo-6 Black Intense Ultra Concentrate within six hours of sleep and points out the need for regular exercise and proper nutrition.

The company also suggests a usage cycle of two months on followed by one month off. Similar recommendations are generally given for most hardcore stimulant-rich fat burners.

Each dose of Lipo-6 Black Intense Ultra Concentrate provides as much caffeine as three cups of coffee. That’s a lot (300 mg +) and the formulation has other stimulants as well.

Not surprisingly, the back of the box bears a warning against using Lipo-6 Black Intense Ultra Concentrate alongside other stimulants or sources of caffeine. 

Lipo-6 Black Intense Ultra Concentrate Ingredients

Each (1-capsule) serving provides 727.5 mg of a proprietary blend.

The proprietary blend contains unspecified amounts of the following six ingredients:

  • Caffeine Anhydrous
  • N-Acetyl-L-Tyrosine
  • Theobromine
  • Paradoxine
  • Rauwolfia Vomitoria Root Extract
  • Yohimbine

Ingredient Value

Although Nutrex Research states the formulation delivers maximum appetite control, that’s unlikely. The formulation lacks any powerful hunger suppressants such as glucomannan or nopal.

Stimulants may help take the edge off hunger, but the level of value they present in this regard varies from person to person. Customer reviews fail to suggest this formulation will offer much help to people who find it hard to keep their appetites under control.

Caffeine Anhydrous

Caffeine is a popular stimulant that’s present in all manner of supplements including diet pills, pre-workouts, and nootropic (brain-boosting) pills.

Although caffeine can cause many side effects, including jitters and nausea, it does not cause problems for most people when included in sensible doses.

It supports weight loss by increasing energy and preventing fatigue. Research show caffeine has additional value as a thermogenic fat burner. 

Most people can tolerate doses of 100-200 mg caffeine. However, Lipo-6 Black Intense Ultra Concentrate provides around 300 mg per capsule and you will be getting it twice per day.

Health experts suggest not consuming more than 400 mg of caffeine per day. Lipo-6 Black Intense Ultra Concentrate provides 50% more and adds additional stimulants on top.


Generally referred to as “NALT,” this ingredient provides the amino acid L-tyrosine. NALT is a common addition to brain-boosting pills but is a less useful inclusion in supplements that aim to help people to lose weight.

Typical NALT benefits include improvements in mental flexibility and comprehension. It may also enhance multi-tasking capabilities.


Theobromine is a cocoa-derived alkaloid and central nervous system stimulant. It’s not as potent as many other stimulants, such as caffeine and bitter orange, so it’s less likely to cause problems.

However, in this formulation, it’s included alongside several more potent stimulants, increasing the overall stimulation effect. That may be unwise.


Paradoxine is a brand of Aframomum melegueta seed extract.

Also known as grains of paradise, Aframomum melegueta is a member of the ginger family. It provides plant chemicals that may support improvements in thermogenesis by converting white adipose tissue (WAT) to brown adipose tissue (BAT).

The value of BAT as an anti-obesity agent is currently under investigation but the outlook so far is promising. 

Rauwolfia Vomitoria Root Extract

Also known as Poison Devil’s Pepper, Rauwolfia vomitoria is a plant that’s native to several countries including Puerto Rico and Tanzania. It provides the stimulant rauwolscine.

Rauwolscine is not one of the more popular supplement ingredients but it’s sometimes present in diet pill formulations. It’s also in some sports supplements.

This ingredient requires further study and, according to WebMD (trusted site), taking it orally may be unsafe. 


Yohimbine is a stimulant sourced from the bark of an African tree. It’s often added to sports supplements and fat burners because it boosts energy levels and metabolism.

Yohimbine is also a popular treatment for erectile dysfunction (ED). It improves erection quality by improving circulation, helping the penis receive a better supply of blood.

Unfortunately, the ingredient also has many known side effects including dizziness, rapid heartbeat, jitters, and mental confusion.

Lipo 6 Black Intense Customer Reviews

Customer reviews are mixed. Some people praise the supplement for its energy-boosting capabilities and there are also reports of weight loss.

However, there are many complaints about side effects. Some reviewers even state the supplement did nothing for them at all.

These people may have built up a higher than normal tolerance to stimulants. This is very common with bodybuilders and other athletes who are used to using stimulant-rich supplements. As the body becomes accustomed to stimulants, they lose their beneficial effects.

A few positive reviews for Lipo-6 Black Intense:

“a great supplement for fat loss. I have lost 14lbs over the last 4 months”

“My starting weight was 209 lbs, I am now 190 lbs and I do not feel as though I have had to had to sacrifice my food or do any strenuous exercise routine”

A few negative reviews on Lipo 6 Black Intense:

“not impressed, I can tolerate coffee but these pills give me the jitters and I cannot sleep at night. I don’t feel as though I have ant weight neither.”

“This stuff is strong but not in a good way. I feel wired all the time but I cannot concentrate. I have not lost a pound in weight”

“Before taking Lipo6 Black I was 177lbs, I am now 176lbs – it has been 4 months. A pound in 4 months c’mon”

Known Side Effects of Lipo 6 Black Intense

Although some customers appear to be able to use the capsules without experiencing any side effects, many people are not so lucky.

Most of the side effects customers report are likely to be stimulant related but others, such as reports of diarrhea, are more surprising and it appears to be quite a common problem.

Some of the other side effects customers report include:

  • Jitters
  • Nausea
  • Nausea/vomiting
  • Fatigue
  • Anxiety
  • Headaches/migraines
  • Rapid heartbeat
  • Difficulty breathing
  • Lightheadedness
  • Insomnia
  • Increases in appetite
  • Weight gain
  • Body pain

Where to Buy Lipo-6 Black Intense Ultra Concentrate

Lipo-6 Black Intense Ultra Concentrate is available from the manufacturer’s website. It’s also possible to buy it via Amazon and any number of online supplement stores. Expect to pay around $40 for a 30-day supply of pills (60 capsules).


Nutrex Research fails to offer customers a money-back guarantee.

Lipo-6 Black Intense Ultra Concentrate Review Conclusion

Nutrex Research does not provide inclusion rates but it admits Lipo-6 Black Intense Ultra Concentrate provides around 300 mg of caffeine per capsule. We feel that is far too much.

Each capsule provides 727.5 mg of active ingredients. Around 427.5 mg of the remaining formulation will consist of NALT, theobromine, Paradoxine, Rauwolfia Vomitoria, and yohimbine. Most of these ingredients are stimulants too, so it’s not surprising many customers report side effects.

The caffeine content alone far exceeds expert recommendations. If you are looking for a good fat burner, we suggest choosing one of our recommended alternatives instead.

Similar Fat Burners to Lipo 6 Black Intense

  • QuadraLean Thermo – a thermogenic fat burner that is similar to Lipo6 Black Intense. See what the differences are.
  • Sculpt Nation Burn PM – a nighttime fat loss pill that can also help with sleep.
  • Hydroxycut Black – another intense weight loss pill that has the same high caffeine content and fat burning message as Lipo6.

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about the author

Henry Washington BSc, BSc, MA, PhD. Fascinated with the study of human behavior, and how this affects our day-to-day lives. Has read more books on the subject than he can count and has an extensive collection of academic papers to match. Published in the following journals: Nature, Journal of Cognitive Neuroscience, Trends in Neurosciences, Neuroscience & Biobehavioral Reviews, Brain research reviews and Cerebral Cortex.